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Senior Scientist I Process Development

Company: St. Jude Children's Research Hospital
Location: Raleigh
Posted on: September 14, 2020

Job Description:

With resources to help you succeed and develop your career, we also offer generous relocation assistance.The Therapeutic Production and Quality department is looking for a Sr. Scientist I Process Development to design and implement process development experiments with minimal supervision, both upstream and downstream unit operations. In this role you will perform small scale culture experiments, set up and run bioreactors for culture of mammalian or bacterial cells, and optimize purification methods using various chromatography techniques. Experience in mammalian cell culture, bioreactors, protein purification (AKTA), tangential flow chromatography and various filtration techniques is preferred. You will generate monoclonal antibodies, recombinant proteins, and gene therapy vectors including Lentiviral and AAV vectors.


  • Maintain processes according to the requirements for drug substances and drug products as mandated by the FDA, EMA and MHRA,
  • Maintain excellent electronic note booking skills and generate reports that summarize all process development activities.
  • Develop production batch records based process development activities in collaboration with the Quality Assurance Department of Children's GMP, LLC. If needed, provide support in cGMP manufacturing.


    • Bachelor's degree in Biological Sciences, Chemical Engineering or Bioprocessing or related field required
    • MS or Ph.D. preferred.


      • Eight (8) years of related experience with a BS.
      • Four (4) years of related experience with a MS.
      • No related experience required with a Ph.D.
      • Experience in process development in a cGMP environment is preferred

        St. Jude is an Equal Opportunity EmployerNo Search Firms:St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

Keywords: St. Jude Children's Research Hospital, Raleigh , Senior Scientist I Process Development, Other , Raleigh, North Carolina

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