Senior Reliability Engineer

Company: Amgen
Location: Holly Springs
Posted on: February 23, 2026

Job Description:

Join Amgens Mission of Serving Patients At Amgen, if you feel likeyourepart of something bigger,itsbecause you are. Our shared missionto serve patients living with serious illnessesdrives all that we do. Since 1980,wevehelped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. As a member of the Amgen team,youllhelp make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities thatliewithin them,youllthrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Be part of Amgen's newest and most advanced drug substance manufacturing plant. When completed, the AmgenFleXBatch facility will combine the latest in disposable technologies with traditional stainless-steel equipment to allow for maximum flexibility in operations. TheFleXBatch facility will not only feature the best in-class drug substance manufacturing technologies with embedded industry 4.0 capabilities, but it will also integrate sustainability innovations to reduce carbon and waste, as part of Amgen's plan to be a carbon-neutral company by 2027. Senior Reliability Engineer In this vital role, you will lead all aspects of the delivery and continuous improvement of the Engineering Asset Management (AM), Reliability, Sustainability, and Continuous Improvement (CI) programs at Amgen North Carolina (ANC). You will serve as the primary system owner and subject matter expert for Engineering AM, CI, alarm management, data analytics, and audit readiness programs, acting as a key liaison between ANC Engineering, Global Asset Management, Sustainability, Quality, and Reliability organizations. The Site Reliability organization will deploy and sustain a comprehensive, standardized Reliability Program aligned with corporate Reliability, Sustainability, and Industry 4.0 strategies. You willestablishand monitor standardized metrics across Manufacturing, Packaging, Laboratories, Maintenance, and Utilities toidentifyperformance gaps, regulatory risks, and major reliability offenders, and to drive data-informed, risk-based improvement plans. Lead Asset Management, Reliability, CI, Sustainability, Alarm Management, and Audit Readiness programs. Establishdata-driven reliability frameworks using analytics, dashboards, and KPIs. Lead MMP activities including PM optimization, job plans, and spare parts strategy. Develop risk-based action plans for reliable and sustainable utilities operations. Own alarm management and alarm review programs aligned with regulatory expectations. Drive sustainability initiatives (energy, waste, lifecycle optimization). Ensure continuous audit readiness and regulatory inspection support. What we expect of you! We are all different, yet we all use our unique contributions to serve patients. The reliability professional we seek is an engineer with these qualifications. Basic Qualifications: High School Diploma / GED and 10 years of Engineering experience OR Associates Degree and 8 years of Engineering experience OR Bachelors Degree and 4 years of Engineering experience OR Masters Degree and 2 years of Engineering experience OR Doctorate Degree Preferred Qualifications: Bachelors degree and 5 years of experience (or equivalent combination). Experience in Reliability Engineering, data analytics, GMP knowledge, sustainability integration, predictive maintenance, alarm management, and audit readiness experience. The ideal individual must be a self-directed excellent teammate ready to mentor and develop engineering staff and embrace a team-based culture that relies on collaboration for effective decision-making. Strong leadership, technical writing, and communication/presentation skills. What you can expect of us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way. In addition to the base salary, Amgen offers competitive and comprehensive Total Rewards Plans that are aligned with local industry standards. Apply now and make a lasting impact with the Amgen team! careers.amgen.com As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Keywords: Amgen, Raleigh , Senior Reliability Engineer, Engineering , Holly Springs, North Carolina